Semaglutide for Weight Loss
A once-weekly GLP-1 injection that helps curb appetite and support steady, sustainable weight loss.
You only pay if you're approved
- Free consultation. No charge unless approved.
- No waiting rooms or pharmacy lines
- Free shipping
- US-licensed clinicians and pharmacies
- Message your care team anytime
Semaglutide is a once-weekly GLP-1 medication used to support weight loss and metabolic health.
Semaglutide mimics a natural gut hormone called GLP-1 that helps regulate appetite and blood sugar.
By signaling fullness to your brain and slowing how quickly your stomach empties, it reduces cravings and the amount you eat — making a reduced-calorie diet easier to sustain.
It's taken as a small injection once a week. Your provider starts you at a low dose and increases it gradually so your body has time to adjust.
The most common are nausea, diarrhea, and constipation.
Other reported side effects include decreased appetite, fatigue, headache, and injection site reactions.
More serious risks — including a warning about thyroid tumors — are covered in detail in our Important Safety Information.
Zanason gives you unlimited messaging with your care team, so you can ask questions any time.
Both are once-weekly injections that support weight loss, but they work differently. Semaglutide is a GLP-1 receptor agonist. Tirzepatide is a dual GIP and GLP-1 receptor agonist, meaning it acts on a second hormone pathway as well. Tirzepatide is typically more expensive, and side effects affect everyone differently.
You'll choose which one you'd like to try in the online questionnaire. Your care team reviews your full health history to confirm it's safe and appropriate before prescribing. You can message your care team anytime with questions, including switching medications if needed.
Compare to Tirzepatide.
We offer formulations paired with either B12 or glycine. The active weight-loss ingredient is semaglutide or tirzepatide—that is what does the heavy lifting either way.
- B12 is a vitamin that supports energy metabolism, which may help keep you feeling energized during your program.
- Glycine is a natural amino acid that serves as a neutral stabilizer for the medication. It doesn't change how the active ingredient works, making it a great option if you prefer a standard formulation without added vitamins.
Nausea is common early on and usually eases after 2–4 weeks at a steady dose. Eat smaller meals, eat slowly, avoid greasy foods, stay hydrated.
Ondansetron is a prescription anti-nausea medication. Your care team can prescribe it if needed — $45/mo for 30 tablets. The option to add ondansetron is included at the end of the online questionnaire.
Yes, in most cases. If you have taken this medication within the past two months, you can generally pick up right where you left off. Simply complete our medical intake form, and our network of licensed providers will evaluate your history to prescribe your matching maintenance dose.
For your safety, if it has been more than two months since your last dose, our providers will likely recommend starting at a lower dose to let your body adjust again. If you are entirely new to this medication, you will begin at the standard starting dose. As a reminder, all doses are the same flat price, so your monthly cost will never go up as your dose changes.
Do not use if you are pregnant, trying to become pregnant, are breastfeeding, or have a personal or family history of medullary thyroid carcinoma or MEN 2. Stop at least 2 months before trying to become pregnant. See Important Safety Information.